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Defining the molecular blueprint that drives CD8(+) T cell differentiation in response to infection

A cardinal feature of adaptive, cytotoxic T lymphocyte (CTL)-mediated immunity is the ability of naïve CTLs to undergo a program of differentiation and proliferation upon activation resulting in the acquisition of lineage-specific T cell functions and eventual establishment of immunological memory....

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Detalles Bibliográficos
Autores principales: Russ, Brendan E., Denton, Alice E., Hatton, Lauren, Croom, Hayley, Olson, Matthew R., Turner, Stephen J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3525900/
https://www.ncbi.nlm.nih.gov/pubmed/23267358
http://dx.doi.org/10.3389/fimmu.2012.00371