Cargando…
ALK receptor activation, ligands and therapeutic targeting in glioblastoma and in other cancers
The intracellular anaplastic lymphoma kinase (ALK) fragment shows striking homology with members of the insulin receptor family and was initially identified as an oncogenic fusion protein resulting from a translocation in lymphoma and more recently in a range of cancers. The full-length ALK transmem...
Autor principal: | |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2012
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3525999/ https://www.ncbi.nlm.nih.gov/pubmed/23267434 http://dx.doi.org/10.3389/fonc.2012.00192 |