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ALK receptor activation, ligands and therapeutic targeting in glioblastoma and in other cancers

The intracellular anaplastic lymphoma kinase (ALK) fragment shows striking homology with members of the insulin receptor family and was initially identified as an oncogenic fusion protein resulting from a translocation in lymphoma and more recently in a range of cancers. The full-length ALK transmem...

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Detalles Bibliográficos
Autor principal: Wellstein, Anton
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3525999/
https://www.ncbi.nlm.nih.gov/pubmed/23267434
http://dx.doi.org/10.3389/fonc.2012.00192