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ABCC4/MRP4: a MYCN-regulated transporter and potential therapeutic target in neuroblastoma

Resistance to cytotoxic drugs is thought to be a major cause of treatment failure in childhood neuroblastoma, and members of the ATP-binding cassette (ABC) transporter superfamily may contribute to this phenomenon by active efflux of chemotherapeutic agents from cancer cells. As a member of the C su...

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Detalles Bibliográficos
Autores principales: Huynh, Tony, Norris, Murray D., Haber, Michelle, Henderson, Michelle J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3526013/
https://www.ncbi.nlm.nih.gov/pubmed/23267433
http://dx.doi.org/10.3389/fonc.2012.00178