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ABCC4/MRP4: a MYCN-regulated transporter and potential therapeutic target in neuroblastoma
Resistance to cytotoxic drugs is thought to be a major cause of treatment failure in childhood neuroblastoma, and members of the ATP-binding cassette (ABC) transporter superfamily may contribute to this phenomenon by active efflux of chemotherapeutic agents from cancer cells. As a member of the C su...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3526013/ https://www.ncbi.nlm.nih.gov/pubmed/23267433 http://dx.doi.org/10.3389/fonc.2012.00178 |