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Hyperglycemia Slows Embryonic Growth and Suppresses Cell Cycle via Cyclin D1 and p21
In pregnant women, the diabetic condition results in a three- to fivefold increased risk for fetal cardiac malformations as a result of elevated glucose concentrations and the resultant osmotic stress in the developing embryo and fetus. Heart development before septation in the chick embryo was stud...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Diabetes Association
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3526024/ https://www.ncbi.nlm.nih.gov/pubmed/23193186 http://dx.doi.org/10.2337/db12-0161 |