Deletion of Skeletal Muscle SOCS3 Prevents Insulin Resistance in Obesity

Obesity is associated with chronic low-grade inflammation that contributes to defects in energy metabolism and insulin resistance. Suppressor of cytokine signaling (SOCS)-3 expression is increased in skeletal muscle of obese humans. SOCS3 inhibits leptin signaling in the hypothalamus and insulin sig...

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Detalles Bibliográficos
Autores principales: Jorgensen, Sebastian Beck, O’Neill, Hayley M., Sylow, Lykke, Honeyman, Jane, Hewitt, Kimberly A., Palanivel, Rengasamy, Fullerton, Morgan D., Öberg, Lisa, Balendran, Anudharan, Galic, Sandra, van der Poel, Chris, Trounce, Ian A., Lynch, Gordon S., Schertzer, Jonathan D., Steinberg, Gregory R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2013
Materias:
Metabolism
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3526029/
https://www.ncbi.nlm.nih.gov/pubmed/22961088
http://dx.doi.org/10.2337/db12-0443

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3526029/
https://www.ncbi.nlm.nih.gov/pubmed/22961088
http://dx.doi.org/10.2337/db12-0443

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