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Bcl-2 and Bcl-x(L) Suppress Glucose Signaling in Pancreatic β-Cells
B-cell lymphoma 2 (Bcl-2) family proteins are established regulators of cell survival, but their involvement in the normal function of primary cells has only recently begun to receive attention. In this study, we demonstrate that chemical and genetic loss-of-function of antiapoptotic Bcl-2 and Bcl-x...
Autores principales: | Luciani, Dan S., White, Sarah A., Widenmaier, Scott B., Saran, Varun V., Taghizadeh, Farnaz, Hu, Xiaoke, Allard, Michael F., Johnson, James D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Diabetes Association
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3526034/ https://www.ncbi.nlm.nih.gov/pubmed/22933114 http://dx.doi.org/10.2337/db11-1464 |
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