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Increased Hepatic Glucose Production in Fetal Sheep With Intrauterine Growth Restriction Is Not Suppressed by Insulin

Intrauterine growth restriction (IUGR) increases the risk for metabolic disease and diabetes, although the developmental origins of this remain unclear. We measured glucose metabolism during basal and insulin clamp periods in a fetal sheep model of placental insufficiency and IUGR. Compared with con...

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Detalles Bibliográficos
Autores principales: Thorn, Stephanie R., Brown, Laura D., Rozance, Paul J., Hay, William W., Friedman, Jacob E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3526037/
https://www.ncbi.nlm.nih.gov/pubmed/22933111
http://dx.doi.org/10.2337/db11-1727