Activation of Enteroendocrine Membrane Progesterone Receptors Promotes Incretin Secretion and Improves Glucose Tolerance in Mice

Glucagon-like peptide-1 (GLP-1) secretion is classically regulated by ingested nutrients. To identify novel molecular targets controlling incretin secretion, we analyzed enteroendocrine cell pathways important for hormone biosynthesis and secretion. We demonstrate that progesterone increases GLP-1 s...

Descripción completa

Detalles Bibliográficos
Autores principales: Flock, Grace B., Cao, Xiemin, Maziarz, Marlena, Drucker, Daniel J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2013
Materias:
Pharmacology and Therapeutics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3526055/
https://www.ncbi.nlm.nih.gov/pubmed/22933106
http://dx.doi.org/10.2337/db12-0601

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3526055/
https://www.ncbi.nlm.nih.gov/pubmed/22933106
http://dx.doi.org/10.2337/db12-0601

Ejemplares similares