C-Peptide Prevents Hyperglycemia-Induced Endothelial Apoptosis Through Inhibition of Reactive Oxygen Species–Mediated Transglutaminase 2 Activation

C-peptide is a bioactive peptide with a potentially protective role in diabetes complications; however, its molecular mechanism of protection against cardiovascular damage caused by hyperglycemia-induced apoptosis remains unclear. We investigated the protective mechanism of C-peptide against hypergl...

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Detalles Bibliográficos
Autores principales: Bhatt, Mahendra Prasad, Lim, Young-Cheol, Hwang, JongYun, Na, SungHun, Kim, Young-Myeong, Ha, Kwon-Soo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3526059/
https://www.ncbi.nlm.nih.gov/pubmed/22923476
http://dx.doi.org/10.2337/db12-0293