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C-Peptide Prevents Hyperglycemia-Induced Endothelial Apoptosis Through Inhibition of Reactive Oxygen Species–Mediated Transglutaminase 2 Activation
C-peptide is a bioactive peptide with a potentially protective role in diabetes complications; however, its molecular mechanism of protection against cardiovascular damage caused by hyperglycemia-induced apoptosis remains unclear. We investigated the protective mechanism of C-peptide against hypergl...
Autores principales: | Bhatt, Mahendra Prasad, Lim, Young-Cheol, Hwang, JongYun, Na, SungHun, Kim, Young-Myeong, Ha, Kwon-Soo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Diabetes Association
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3526059/ https://www.ncbi.nlm.nih.gov/pubmed/22923476 http://dx.doi.org/10.2337/db12-0293 |
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