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Polymorphisms of arylamine N-acetyltransferase2 and risk of lung and colorectal cancer

The arylamine N-acetyltransferase 2 (NAT2) enzymes detoxify a wide range of naturally occurring xenobiotics including carcinogens and drugs. Point mutations in the NAT2 gene result in the variant alleles M1 (NAT2 *5A), M2 (NAT2*6A), M3 (NAT2*7) and M4 (NAT2 *14A) from the wild-type WT (NAT2 *4) alle...

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Detalles Bibliográficos
Autores principales: Mahasneh, Amjad, Jubaili, Amal, El Bateiha, Ahmed, Al-Ghazo, Mohammad, Matalka, Ismail, Malkawi, Mousa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Genética 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3526077/
https://www.ncbi.nlm.nih.gov/pubmed/23271930
http://dx.doi.org/10.1590/S1415-47572012005000074