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Polymorphisms of arylamine N-acetyltransferase2 and risk of lung and colorectal cancer
The arylamine N-acetyltransferase 2 (NAT2) enzymes detoxify a wide range of naturally occurring xenobiotics including carcinogens and drugs. Point mutations in the NAT2 gene result in the variant alleles M1 (NAT2 *5A), M2 (NAT2*6A), M3 (NAT2*7) and M4 (NAT2 *14A) from the wild-type WT (NAT2 *4) alle...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Sociedade Brasileira de Genética
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3526077/ https://www.ncbi.nlm.nih.gov/pubmed/23271930 http://dx.doi.org/10.1590/S1415-47572012005000074 |