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LCR 5′ hypersensitive site specificity for globin gene activation within the active chromatin hub

The DNaseI hypersensitive sites (HSs) of the human β-globin locus control region (LCR) may function as part of an LCR holocomplex within a larger active chromatin hub (ACH). Differential activation of the globin genes during development may be controlled in part by preferential interaction of each g...

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Detalles Bibliográficos
Autores principales: Peterson, Kenneth R., Fedosyuk, Halyna, Harju-Baker, Susanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3526258/
https://www.ncbi.nlm.nih.gov/pubmed/23042246
http://dx.doi.org/10.1093/nar/gks900