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LCR 5′ hypersensitive site specificity for globin gene activation within the active chromatin hub
The DNaseI hypersensitive sites (HSs) of the human β-globin locus control region (LCR) may function as part of an LCR holocomplex within a larger active chromatin hub (ACH). Differential activation of the globin genes during development may be controlled in part by preferential interaction of each g...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3526258/ https://www.ncbi.nlm.nih.gov/pubmed/23042246 http://dx.doi.org/10.1093/nar/gks900 |