Cargando…
Evaluation of single CpG sites as proxies of CpG island methylation states at the genome scale
Methylation of a CpG island is a faithful marker of silencing of its associated gene. Different approaches report the methylation status of a CpG island based on the determination of one or a few CpG sites by assuming the homogeneity of methylation along the element. This strategy is frequently appl...
Autores principales: | , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2012
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3526261/ https://www.ncbi.nlm.nih.gov/pubmed/23066096 http://dx.doi.org/10.1093/nar/gks928 |