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Evaluation of single CpG sites as proxies of CpG island methylation states at the genome scale
Methylation of a CpG island is a faithful marker of silencing of its associated gene. Different approaches report the methylation status of a CpG island based on the determination of one or a few CpG sites by assuming the homogeneity of methylation along the element. This strategy is frequently appl...
Autores principales: | Barrera, Víctor, Peinado, Miguel A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3526261/ https://www.ncbi.nlm.nih.gov/pubmed/23066096 http://dx.doi.org/10.1093/nar/gks928 |
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