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The C-terminus of Dpb2 is required for interaction with Pol2 and for cell viability

DNA polymerase ε (Pol ε) participates in the synthesis of the leading strand during DNA replication in Saccharomyces cerevisiae. Pol ε comprises four subunits: the catalytic subunit, Pol2, and three accessory subunits, Dpb2, Dpb3 and Dpb4. DPB2 is an essential gene with unclear function. A genetic s...

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Detalles Bibliográficos
Autores principales: Isoz, Isabelle, Persson, Ulf, Volkov, Kirill, Johansson, Erik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3526264/
https://www.ncbi.nlm.nih.gov/pubmed/23034803
http://dx.doi.org/10.1093/nar/gks880