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Pmt1, a Dnmt2 homolog in Schizosaccharomyces pombe, mediates tRNA methylation in response to nutrient signaling

The fission yeast Schizosaccharomyces pombe carries a cytosine 5-methyltransferase homolog of the Dnmt2 family (termed pombe methyltransferase 1, Pmt1), but contains no detectable DNA methylation. Here, we found that Pmt1, like other Dnmt2 homologs, has in vitro methylation activity on cytosine 38 o...

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Detalles Bibliográficos
Autores principales: Becker, Maria, Müller, Sara, Nellen, Wolfgang, Jurkowski, Tomasz P., Jeltsch, Albert, Ehrenhofer-Murray, Ann E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3526270/
https://www.ncbi.nlm.nih.gov/pubmed/23074192
http://dx.doi.org/10.1093/nar/gks956