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Direct quantitative analysis of HCV RNA by atomic force microscopy without labeling or amplification
Force-based atomic force microscopy (AFM) was used to detect HCV (hepatitis C virus) RNA directly and to quantitatively analyse it without the need for reverse transcription or amplification. Capture and detection DNA probes were designed. The former was spotted onto a substrate with a conventional...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3526272/ https://www.ncbi.nlm.nih.gov/pubmed/23074195 http://dx.doi.org/10.1093/nar/gks953 |