Direct quantitative analysis of HCV RNA by atomic force microscopy without labeling or amplification

Force-based atomic force microscopy (AFM) was used to detect HCV (hepatitis C virus) RNA directly and to quantitatively analyse it without the need for reverse transcription or amplification. Capture and detection DNA probes were designed. The former was spotted onto a substrate with a conventional...

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Detalles Bibliográficos
Autores principales: Jung, Yu Jin, Albrecht, Jeffrey A., Kwak, Ju-Won, Park, Joon Won
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3526272/
https://www.ncbi.nlm.nih.gov/pubmed/23074195
http://dx.doi.org/10.1093/nar/gks953

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