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Self-organization of domain structures by DNA-loop-extruding enzymes

The long chromosomal DNAs of cells are organized into loop domains much larger in size than individual DNA-binding enzymes, presenting the question of how formation of such structures is controlled. We present a model for generation of defined chromosomal loops, based on molecular machines consistin...

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Detalles Bibliográficos
Autores principales: Alipour, Elnaz, Marko, John F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3526278/
https://www.ncbi.nlm.nih.gov/pubmed/23074191
http://dx.doi.org/10.1093/nar/gks925