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DNA-binding determinants promoting NHEJ by human Polµ

Non-homologous end-joining (NHEJ), the preferred pathway to repair double-strand breaks (DSBs) in higher eukaryotes, relies on a collection of molecular tools to process the broken ends, including specific DNA polymerases. Among them, Polµ is unique as it can catalyze DNA synthesis upon connection o...

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Detalles Bibliográficos
Autores principales: Martin, Maria Jose, Juarez, Raquel, Blanco, Luis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3526283/
https://www.ncbi.nlm.nih.gov/pubmed/23034807
http://dx.doi.org/10.1093/nar/gks896