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A subcomplex of human mitochondrial RNase P is a bifunctional methyltransferase—extensive moonlighting in mitochondrial tRNA biogenesis

Transfer RNAs (tRNAs) reach their mature functional form through several steps of processing and modification. Some nucleotide modifications affect the proper folding of tRNAs, and they are crucial in case of the non-canonically structured animal mitochondrial tRNAs, as exemplified by the apparently...

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Detalles Bibliográficos
Autores principales: Vilardo, Elisa, Nachbagauer, Christa, Buzet, Aurélie, Taschner, Andreas, Holzmann, Johann, Rossmanith, Walter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3526285/
https://www.ncbi.nlm.nih.gov/pubmed/23042678
http://dx.doi.org/10.1093/nar/gks910