AIRE-PHD fingers are structural hubs to maintain the integrity of chromatin-associated interactome

Mutations in autoimmune regulator (AIRE) gene cause autoimmune polyendocrinopathy candidiasis ectodermal dystrophy. AIRE is expressed in thymic medullary epithelial cells, where it promotes the expression of peripheral-tissue antigens to mediate deletional tolerance, thereby preventing self-reactivi...

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Detalles Bibliográficos
Autores principales: Gaetani, Massimiliano, Matafora, Vittoria, Saare, Mario, Spiliotopoulos, Dimitrios, Mollica, Luca, Quilici, Giacomo, Chignola, Francesca, Mannella, Valeria, Zucchelli, Chiara, Peterson, Pärt, Bachi, Angela, Musco, Giovanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3526288/
https://www.ncbi.nlm.nih.gov/pubmed/23074189
http://dx.doi.org/10.1093/nar/gks933

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3526288/
https://www.ncbi.nlm.nih.gov/pubmed/23074189
http://dx.doi.org/10.1093/nar/gks933

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