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The folding of the hepatitis C virus internal ribosome entry site depends on the 3′-end of the viral genome
Hepatitis C virus (HCV) translation initiation is directed by an internal ribosome entry site (IRES) and regulated by distant regions at the 3′-end of the viral genome. Through a combination of improved RNA chemical probing methods, SHAPE structural analysis and screening of RNA accessibility using...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3526292/ https://www.ncbi.nlm.nih.gov/pubmed/23066110 http://dx.doi.org/10.1093/nar/gks927 |