Hundreds of conserved non-coding genomic regions are independently lost in mammals

Conserved non-protein-coding DNA elements (CNEs) often encode cis-regulatory elements and are rarely lost during evolution. However, CNE losses that do occur can be associated with phenotypic changes, exemplified by pelvic spine loss in sticklebacks. Using a computational strategy to detect complete...

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Detalles Bibliográficos
Autores principales: Hiller, Michael, Schaar, Bruce T., Bejerano, Gill
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Genomics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3526296/
https://www.ncbi.nlm.nih.gov/pubmed/23042682
http://dx.doi.org/10.1093/nar/gks905

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3526296/
https://www.ncbi.nlm.nih.gov/pubmed/23042682
http://dx.doi.org/10.1093/nar/gks905

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