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Hundreds of conserved non-coding genomic regions are independently lost in mammals
Conserved non-protein-coding DNA elements (CNEs) often encode cis-regulatory elements and are rarely lost during evolution. However, CNE losses that do occur can be associated with phenotypic changes, exemplified by pelvic spine loss in sticklebacks. Using a computational strategy to detect complete...
Autores principales: | Hiller, Michael, Schaar, Bruce T., Bejerano, Gill |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3526296/ https://www.ncbi.nlm.nih.gov/pubmed/23042682 http://dx.doi.org/10.1093/nar/gks905 |
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