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DNA catenation maintains structure of human metaphase chromosomes

Mitotic chromosome structure is pivotal to cell division but difficult to observe in fine detail using conventional methods. DNA catenation has been implicated in both sister chromatid cohesion and chromosome condensation, but has never been observed directly. We have used a lab-on-a-chip microfluid...

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Detalles Bibliográficos
Autores principales: Bauer, David L. V., Marie, Rodolphe, Rasmussen, Kristian H., Kristensen, Anders, Mir, Kalim U.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3526300/
https://www.ncbi.nlm.nih.gov/pubmed/23066100
http://dx.doi.org/10.1093/nar/gks931