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Targeted manipulation of heterochromatin rescues MeCP2 Rett mutants and re-establishes higher order chromatin organization

Heterochromatic regions represent a significant portion of the mammalian genome and have been implied in several important cellular processes, including cell division and genomic stability. However, its composition and dynamics remain largely unknown. To better understand how heterochromatin functio...

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Detalles Bibliográficos
Autores principales: Casas-Delucchi, Corella S., Becker, Annette, Bolius, Janine J., Cardoso, M. Cristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3526307/
https://www.ncbi.nlm.nih.gov/pubmed/22923521
http://dx.doi.org/10.1093/nar/gks784