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RNA-binding protein AUF1 represses Dicer expression

MicroRNA (miRNA) biogenesis is tightly regulated by numerous proteins. Among them, Dicer is required for the processing of the precursor (pre-)miRNAs into the mature miRNA. Despite its critical function, the mechanisms that regulate Dicer expression are not well understood. Here we report that the R...

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Detalles Bibliográficos
Autores principales: Abdelmohsen, Kotb, Tominaga-Yamanaka, Kumiko, Srikantan, Subramanya, Yoon, Je-Hyun, Kang, Min-Ju, Gorospe, Myriam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3526313/
https://www.ncbi.nlm.nih.gov/pubmed/23066106
http://dx.doi.org/10.1093/nar/gks930