Improved predictions of transcription factor binding sites using physicochemical features of DNA

Typical approaches for predicting transcription factor binding sites (TFBSs) involve use of a position-specific weight matrix (PWM) to statistically characterize the sequences of the known sites. Recently, an alternative physicochemical approach, called SiteSleuth, was proposed. In this approach, a...

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Detalles Bibliográficos
Autores principales: Maienschein-Cline, Mark, Dinner, Aaron R., Hlavacek, William S., Mu, Fangping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Methods Online
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3526315/
https://www.ncbi.nlm.nih.gov/pubmed/22923524
http://dx.doi.org/10.1093/nar/gks771

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3526315/
https://www.ncbi.nlm.nih.gov/pubmed/22923524
http://dx.doi.org/10.1093/nar/gks771

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