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Improved predictions of transcription factor binding sites using physicochemical features of DNA
Typical approaches for predicting transcription factor binding sites (TFBSs) involve use of a position-specific weight matrix (PWM) to statistically characterize the sequences of the known sites. Recently, an alternative physicochemical approach, called SiteSleuth, was proposed. In this approach, a...
Autores principales: | Maienschein-Cline, Mark, Dinner, Aaron R., Hlavacek, William S., Mu, Fangping |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3526315/ https://www.ncbi.nlm.nih.gov/pubmed/22923524 http://dx.doi.org/10.1093/nar/gks771 |
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