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Antibody orientation at bacterial surfaces is related to invasive infection

Several of the most significant bacterial pathogens in humans, including Streptococcus pyogenes, express surface proteins that bind IgG antibodies via their fragment crystallizable (Fc) region, and the dogma is that this protects the bacteria against phagocytic killing in blood. However, analysis of...

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Detalles Bibliográficos
Autores principales: Nordenfelt, Pontus, Waldemarson, Sofia, Linder, Adam, Mörgelin, Matthias, Karlsson, Christofer, Malmström, Johan, Björck, Lars
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3526361/
https://www.ncbi.nlm.nih.gov/pubmed/23230002
http://dx.doi.org/10.1084/jem.20120325