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Antibody orientation at bacterial surfaces is related to invasive infection
Several of the most significant bacterial pathogens in humans, including Streptococcus pyogenes, express surface proteins that bind IgG antibodies via their fragment crystallizable (Fc) region, and the dogma is that this protects the bacteria against phagocytic killing in blood. However, analysis of...
Autores principales: | Nordenfelt, Pontus, Waldemarson, Sofia, Linder, Adam, Mörgelin, Matthias, Karlsson, Christofer, Malmström, Johan, Björck, Lars |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3526361/ https://www.ncbi.nlm.nih.gov/pubmed/23230002 http://dx.doi.org/10.1084/jem.20120325 |
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