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Sustained effector function of IL-12/15/18–preactivated NK cells against established tumors

Natural killer cell (NK cell)–based immunotherapy of cancer is hampered by the transient effector function of NK cells. Recently, mouse IL-12/15/18–preactivated NK cells were shown to persist with sustained effector function in vivo. Our study investigated the antitumor activity of such NK cells. A...

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Detalles Bibliográficos
Autores principales: Ni, Jing, Miller, Matthias, Stojanovic, Ana, Garbi, Natalio, Cerwenka, Adelheid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3526364/
https://www.ncbi.nlm.nih.gov/pubmed/23209317
http://dx.doi.org/10.1084/jem.20120944