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Sustained effector function of IL-12/15/18–preactivated NK cells against established tumors
Natural killer cell (NK cell)–based immunotherapy of cancer is hampered by the transient effector function of NK cells. Recently, mouse IL-12/15/18–preactivated NK cells were shown to persist with sustained effector function in vivo. Our study investigated the antitumor activity of such NK cells. A...
Autores principales: | Ni, Jing, Miller, Matthias, Stojanovic, Ana, Garbi, Natalio, Cerwenka, Adelheid |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3526364/ https://www.ncbi.nlm.nih.gov/pubmed/23209317 http://dx.doi.org/10.1084/jem.20120944 |
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