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Bcl11a is essential for lymphoid development and negatively regulates p53

Transcription factors play important roles in lymphopoiesis. We have previously demonstrated that Bcl11a is essential for normal lymphocyte development in the mouse embryo. We report here that, in the adult mouse, Bcl11a is expressed in most hematopoietic cells and is highly enriched in B cells, ear...

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Detalles Bibliográficos
Autores principales: Yu, Yong, Wang, Juexuan, Khaled, Walid, Burke, Shannon, Li, Peng, Chen, Xiongfeng, Yang, Wei, Jenkins, Nancy A., Copeland, Neal G., Zhang, Shujun, Liu, Pentao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3526365/
https://www.ncbi.nlm.nih.gov/pubmed/23230003
http://dx.doi.org/10.1084/jem.20121846