Cargando…

Bcl11a is essential for lymphoid development and negatively regulates p53

Transcription factors play important roles in lymphopoiesis. We have previously demonstrated that Bcl11a is essential for normal lymphocyte development in the mouse embryo. We report here that, in the adult mouse, Bcl11a is expressed in most hematopoietic cells and is highly enriched in B cells, ear...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yu, Yong, Wang, Juexuan, Khaled, Walid, Burke, Shannon, Li, Peng, Chen, Xiongfeng, Yang, Wei, Jenkins, Nancy A., Copeland, Neal G., Zhang, Shujun, Liu, Pentao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2012
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3526365/ https://www.ncbi.nlm.nih.gov/pubmed/23230003 http://dx.doi.org/10.1084/jem.20121846

Ejemplares similares

The transcription factor Bcl11b is specifically expressed in group 2 innate lymphoid cells and is essential for their development
por: Yu, Yong, et al.
Publicado: (2015)

BCL11A is a triple-negative breast cancer gene with critical functions in stem and progenitor cells
por: Khaled, Walid T., et al.
Publicado: (2015)

BCL11B is required for positive selection and survival of double-positive thymocytes
por: Albu, Diana I., et al.
Publicado: (2007)

Bcl11b is essential for group 2 innate lymphoid cell development
por: Walker, Jennifer A., et al.
Publicado: (2015)

A dual function of Bcl11b/Ctip2 in hippocampal neurogenesis
por: Simon, Ruth, et al.
Publicado: (2012)

Stability and Function of Hippocampal Mossy Fiber Synapses Depend on Bcl11b/Ctip2
por: De Bruyckere, Elodie, et al.
Publicado: (2018)

Critical role of Bcl11b in suppressor function of T regulatory cells and prevention of inflammatory bowel disease
por: VanValkenburgh, Jeffrey, et al.
Publicado: (2011)

Antigen-specific clonal expansion and cytolytic effector function of CD8(+) T lymphocytes depend on the transcription factor Bcl11b
por: Zhang, Shuning, et al.
Publicado: (2010)

Developmental cell death of cortical projection neurons is controlled by a Bcl11a/Bcl6‐dependent pathway
por: Wiegreffe, Christoph, et al.
Publicado: (2022)

Single-cell transcriptomic reconstruction reveals cell cycle and multi-lineage differentiation defects in Bcl11a-deficient hematopoietic stem cells
por: Tsang, Jason C. H., et al.
Publicado: (2015)

Functional characterization of common BCL11B gene desert variants suggests a lymphocyte-mediated association of BCL11B with aortic stiffness
por: Maskari, Raya Al, et al.
Publicado: (2018)

BCL11A interacts with SOX2 to control the expression of epigenetic regulators in lung squamous carcinoma
por: Lazarus, Kyren A., et al.
Publicado: (2018)

BCL11A Promotes the Progression of Laryngeal Squamous Cell Carcinoma
por: Zhou, Jian, et al.
Publicado: (2020)

Bcl11a Controls Flt3 Expression in Early Hematopoietic Progenitors and Is Required for pDC Development In Vivo
por: Wu, Xiaodi, et al.
Publicado: (2013)

Cell type–specific actions of Bcl11b in early T-lineage and group 2 innate lymphoid cells
por: Hosokawa, Hiroyuki, et al.
Publicado: (2019)

Structure‐function integrity of the adult hippocampus depends on the transcription factor Bcl11b/Ctip2
por: Simon, R., et al.
Publicado: (2016)

Molecular Cloning and Biological Characterization of a Novel Murine Lymphoid Growth Factor
por: Sims, John E., et al.
Publicado: (2000)

Structures of p53/BCL-2 complex suggest a mechanism for p53 to antagonize BCL-2 activity
por: Wei, Hudie, et al.
Publicado: (2023)

BCL11A Haploinsufficiency Causes an Intellectual Disability Syndrome and Dysregulates Transcription
por: Dias, Cristina, et al.
Publicado: (2016)

380 The kinesin-like protein Kif11 is essential for the survival of TP53 mutant triple-negative breast cancer cells
por: Lanier, Amanda, et al.
Publicado: (2023)

Role of the CARMA1/BCL10/MALT1 complex in lymphoid malignancies
por: Juilland, Mélanie, et al.
Publicado: (2016)

Bcl11b is essential for licensing Th2 differentiation during helminth infection and allergic asthma
por: Lorentsen, Kyle J., et al.
Publicado: (2018)

BCL11B suppresses tumor progression and stem cell traits in hepatocellular carcinoma by restoring p53 signaling activity
por: Yang, Wen-Jing, et al.
Publicado: (2020)

SAT-008 Overcoming BCL-2 Resistance in Glucocorticoid-Treated Tumor Lymphoid Cells
por: Bortner, Carl, et al.
Publicado: (2019)

Hyperphosphorylation of BCL-2 family proteins underlies functional resistance to venetoclax in lymphoid malignancies
por: Chong, Stephen Jun Fei, et al.
Publicado: (2023)

Bcl11b, a novel GATA3-interacting protein, suppresses Th1 while limiting Th2 cell differentiation
por: Fang, Difeng, et al.
Publicado: (2018)

Identification of cancer driver genes using Sleeping Beauty transposon mutagenesis
por: Takeda, Haruna, et al.
Publicado: (2021)

p53, Bcl-2 and C-Myc Expressions in Colorectal Carcinoma Associated with Schistosomiasis in Egypt
por: Zalata, Khaled R., et al.
Publicado: (2005)

The role of BCL11B in hematological malignancy
por: Huang, Xin, et al.
Publicado: (2012)

Evolution of nanobodies specific for BCL11A
por: Yin, Maolu, et al.
Publicado: (2023)

BCL11A Expression in Breast Cancer
por: Kątnik, Ewa, et al.
Publicado: (2023)

Expression of Bcl-2 and p53 at the fetal-maternal interface of rhesus monkey
por: Wei, Peng, et al.
Publicado: (2005)

Expression of bcl-2 and p53 in bovine cutaneous fibropapillomas
por: Bocaneti, Florentina, et al.
Publicado: (2015)

Publisher Correction: Bcl11b is essential for licensing Th2 differentiation during helminth infection and allergic asthma
por: Lorentsen, Kyle J., et al.
Publicado: (2018)

BCL11A confers cell invasion and migration in androgen receptor-positive triple-negative breast cancer
por: Wang, Xin, et al.
Publicado: (2020)

bcl-2 overexpression combined with p53 protein accumulation correlates with hormone-refractory prostate cancer.
por: Apakama, I., et al.
Publicado: (1996)

The Analysis of bcl-2 in Association with p53 and Ki-67 in Triple Negative Breast Cancer and Other Molecular Subtypes in Ghana
por: Ameh-Mensah, Charity, et al.
Publicado: (2021)

BCL10-CARD11 Fusion Mimics an Active CARD11 Seed That Triggers Constitutive BCL10 Oligomerization and Lymphocyte Activation
por: Seeholzer, Thomas, et al.
Publicado: (2018)

Functional studies of BCL11A: characterization of the conserved BCL11A-XL splice variant and its interaction with BCL6 in nuclear paraspeckles of germinal center B cells
por: Liu, Hui, et al.
Publicado: (2006)

Identification of BCL11B as a regulator of adipogenesis
por: Inoue, Jun, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_iu9o6f42f5scpmv1b56evkehoj