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SOD1 aggregation in astrocytes following ischemia/reperfusion injury: a role of NO-mediated S-nitrosylation of protein disulfide isomerase (PDI)

BACKGROUND: Ubiquitinated-protein aggregates are implicated in cerebral ischemia/reperfusion injury. The very presence of these ubiquitinated-protein aggregates is abnormal and seems to be disease-related. However, it is not clear what leads to aggregate formation and whether the aggregations repres...

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Detalles Bibliográficos
Autores principales: Chen, Xueping, Guan, Teng, Li, Chen, Shang, Huifang, Cui, Liying, Li, Xin-Min, Kong, Jiming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3526400/
https://www.ncbi.nlm.nih.gov/pubmed/23061969
http://dx.doi.org/10.1186/1742-2094-9-237