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SOD1 aggregation in astrocytes following ischemia/reperfusion injury: a role of NO-mediated S-nitrosylation of protein disulfide isomerase (PDI)
BACKGROUND: Ubiquitinated-protein aggregates are implicated in cerebral ischemia/reperfusion injury. The very presence of these ubiquitinated-protein aggregates is abnormal and seems to be disease-related. However, it is not clear what leads to aggregate formation and whether the aggregations repres...
Autores principales: | Chen, Xueping, Guan, Teng, Li, Chen, Shang, Huifang, Cui, Liying, Li, Xin-Min, Kong, Jiming |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3526400/ https://www.ncbi.nlm.nih.gov/pubmed/23061969 http://dx.doi.org/10.1186/1742-2094-9-237 |
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