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Exploiting ancestral mammalian genomes for the prediction of human transcription factor binding sites

BACKGROUND: The computational prediction of Transcription Factor Binding Sites (TFBS) remains a challenge due to their short length and low information content. Comparative genomics approaches that simultaneously consider several related species and favor sites that have been conserved throughout ev...

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Detalles Bibliográficos
Autor principal: Blanchette, Mathieu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3526440/
https://www.ncbi.nlm.nih.gov/pubmed/23281809
http://dx.doi.org/10.1186/1471-2105-13-S19-S2