The gamma chain subunit of Fc receptors is required for alpha-synuclein-induced pro-inflammatory signaling in microglia

BACKGROUND: The protein alpha-synuclein (α-SYN), which is found in the Lewy bodies of dopamine-producing (DA) neurons in the substantia nigra (SN), has an important role in the pathogenesis of Parkinson’s disease (PD). Previous studies have shown that neuroinflammation plays a key role in PD pathoge...

Descripción completa

Detalles Bibliográficos
Autores principales: Cao, Shuwen, Standaert, David G, Harms, Ashley S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3526448/
https://www.ncbi.nlm.nih.gov/pubmed/23186369
http://dx.doi.org/10.1186/1742-2094-9-259

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3526448/
https://www.ncbi.nlm.nih.gov/pubmed/23186369
http://dx.doi.org/10.1186/1742-2094-9-259

Ejemplares similares