Mineralocorticoid and glucocorticoid receptors differentially regulate NF-kappaB activity and pro-inflammatory cytokine production in murine BV-2 microglial cells

BACKGROUND: Microglia, the resident macrophage-like cells in the brain, regulate innate immune responses in the CNS to protect neurons. However, excessive activation of microglia contributes to neurodegenerative diseases. Corticosteroids are potent modulators of inflammation and mediate their effect...

Descripción completa

Detalles Bibliográficos
Autores principales: Chantong, Boonrat, Kratschmar, Denise V, Nashev, Lyubomir G, Balazs, Zoltan, Odermatt, Alex
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3526453/
https://www.ncbi.nlm.nih.gov/pubmed/23190711
http://dx.doi.org/10.1186/1742-2094-9-260

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3526453/
https://www.ncbi.nlm.nih.gov/pubmed/23190711
http://dx.doi.org/10.1186/1742-2094-9-260

Ejemplares similares