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Differentiation-Associated Reprogramming of the Transforming Growth Factor β Receptor Pathway Establishes the Circuitry for Epithelial Autocrine/Paracrine Repair

Transforming growth factor (TGF) β has diverse and sometimes paradoxical effects on cell proliferation and differentiation, presumably reflecting a fundamental but incompletely-understood role in regulating tissue homeostasis. It is generally considered that downstream activity is modulated at the l...

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Detalles Bibliográficos
Autores principales: Fleming, Jonathan M., Shabir, Saqib, Varley, Claire L., Kirkwood, Lisa A., White, Angela, Holder, Julie, Trejdosiewicz, Ludwik K., Southgate, Jennifer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3526617/
https://www.ncbi.nlm.nih.gov/pubmed/23284691
http://dx.doi.org/10.1371/journal.pone.0051404