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Differentiation-Associated Reprogramming of the Transforming Growth Factor β Receptor Pathway Establishes the Circuitry for Epithelial Autocrine/Paracrine Repair
Transforming growth factor (TGF) β has diverse and sometimes paradoxical effects on cell proliferation and differentiation, presumably reflecting a fundamental but incompletely-understood role in regulating tissue homeostasis. It is generally considered that downstream activity is modulated at the l...
Autores principales: | Fleming, Jonathan M., Shabir, Saqib, Varley, Claire L., Kirkwood, Lisa A., White, Angela, Holder, Julie, Trejdosiewicz, Ludwik K., Southgate, Jennifer |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3526617/ https://www.ncbi.nlm.nih.gov/pubmed/23284691 http://dx.doi.org/10.1371/journal.pone.0051404 |
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