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Hybrid Mathematical Model of Cardiomyocyte Turnover in the Adult Human Heart

RATIONALE: The capacity for cardiomyocyte regeneration in the healthy adult human heart is fundamentally relevant for both myocardial homeostasis and cardiomyopathy therapeutics. However, estimates of cardiomyocyte turnover rates conflict greatly, with a study employing C14 pulse-chase methodology c...

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Detalles Bibliográficos
Autores principales: Elser, Jeremy A., Margulies, Kenneth B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3526650/
https://www.ncbi.nlm.nih.gov/pubmed/23284740
http://dx.doi.org/10.1371/journal.pone.0051683