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Hybrid Mathematical Model of Cardiomyocyte Turnover in the Adult Human Heart
RATIONALE: The capacity for cardiomyocyte regeneration in the healthy adult human heart is fundamentally relevant for both myocardial homeostasis and cardiomyopathy therapeutics. However, estimates of cardiomyocyte turnover rates conflict greatly, with a study employing C14 pulse-chase methodology c...
Autores principales: | Elser, Jeremy A., Margulies, Kenneth B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3526650/ https://www.ncbi.nlm.nih.gov/pubmed/23284740 http://dx.doi.org/10.1371/journal.pone.0051683 |
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