Highly potent VEGF-A-antagonistic DARPins as anti-angiogenic agents for topical and intravitreal applications

The next-generation ophthalmic anti-VEGF therapeutics must aim at being superior to the currently available agents with regard to potency and improved drug delivery, while still being stable and safe to use at elevated concentrations. We show here the generation of a set of highly potent VEGF-A anta...

Descripción completa

Detalles Bibliográficos
Autores principales: Stahl, Andreas, Stumpp, Michael T., Schlegel, Anja, Ekawardhani, Savira, Lehrling, Christina, Martin, Gottfried, Gulotti-Georgieva, Maya, Villemagne, Denis, Forrer, Patrik, Agostini, Hansjürgen T., Binz, H. Kaspar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2012
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3526737/
https://www.ncbi.nlm.nih.gov/pubmed/22983424
http://dx.doi.org/10.1007/s10456-012-9302-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3526737/
https://www.ncbi.nlm.nih.gov/pubmed/22983424
http://dx.doi.org/10.1007/s10456-012-9302-0

Ejemplares similares