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Neonatal DSP-4 Treatment Modifies Antinociceptive Effects of the CB(1) Receptor Agonist Methanandamide in Adult Rats

To study the influence of the central noradrenergic system on antinociceptive effects mediated by the CB(1)-receptor agonist methanandamide, intact rats were contrasted with rats in which noradrenergic nerves were largely destroyed shortly after birth with the neurotoxin DSP-4 [N-(-2-chloroethyl)-N-...

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Detalles Bibliográficos
Autores principales: Korossy-Mruk, Eva, Kuter, Katarzyna, Nowak, Przemysław, Szkilnik, Ryszard, Rykaczewska-Czerwinska, Monika, Kostrzewa, Richard M., Brus, Ryszard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3526738/
https://www.ncbi.nlm.nih.gov/pubmed/22488162
http://dx.doi.org/10.1007/s12640-012-9323-x