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Multiple Signaling Molecules are Involved in Expression of CCL2 and IL-1β in Response to FSL-1, a Toll-Like Receptor 6 Agonist, in Macrophages

TLR6 forms a heterodimer with TLR2 and TLR4. While proinflammatory roles of TLR2 and TLR4 are well documented, the role of TLR6 in inflammation is poorly understood. In order to understand mechanisms of action of TLR6 in inflammatory responses, we investigated the effects of FSL-1, the TLR6 ligand,...

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Detalles Bibliográficos
Autores principales: Won, Keunsoo, Kim, Sun-Mi, Lee, Sae-A, Rhim, Byung-Yong, Eo, Seong-Kug, Kim, Koanhoi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Physiological Society and The Korean Society of Pharmacology 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3526750/
https://www.ncbi.nlm.nih.gov/pubmed/23271927
http://dx.doi.org/10.4196/kjpp.2012.16.6.447