Structures of Lysenin Reveal a Shared Evolutionary Origin for Pore-Forming Proteins And Its Mode of Sphingomyelin Recognition

Pore-forming proteins insert from solution into membranes to create lesions, undergoing a structural rearrangement often accompanied by oligomerization. Lysenin, a pore-forming toxin from the earthworm Eisenia fetida, specifically interacts with sphingomyelin (SM) and may confer innate immunity agai...

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Detalles Bibliográficos
Autores principales: De Colibus, Luigi, Sonnen, Andreas F.-P., Morris, Keith J., Siebert, C. Alistair, Abrusci, Patrizia, Plitzko, Jürgen, Hodnik, Vesna, Leippe, Matthias, Volpi, Emanuela, Anderluh, Gregor, Gilbert, Robert J.C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3526787/
https://www.ncbi.nlm.nih.gov/pubmed/22819216
http://dx.doi.org/10.1016/j.str.2012.06.011

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3526787/
https://www.ncbi.nlm.nih.gov/pubmed/22819216
http://dx.doi.org/10.1016/j.str.2012.06.011

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